Articles: sars-cov-2.
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The nationwide lockdowns ended influenza seasons rapidly in Northern Hemisphere in Spring 2020. The strategy during the second wave was to minimize the restrictions set for children. Children spread influenza and therefore simultaneous influenza and COVID-19 surges were feared. ⋯ In the three preceding years, the numbers and corresponding incidences from August to March were 12 461 (282 per 100 000 person-years) in 2019-2020, 15 276 (346 per 100 000 person-years) in 2018-2019, and 33 659 (761 per 100 000 person-years) in 2017-2018. Nonpharmaceutical interventions combined with the lockdown measures interrupted the influenza season in Finland in March 2020. Despite looser restrictions, alongside traveling restrictions and facial masks, failing to prevent the spread of the severe acute respiratory syndrome coronavirus 2 virus, these restrictions have proved to be effective against seasonal influenza.
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Clin. Microbiol. Infect. · Sep 2021
SARS-CoV-2 antibody dynamics and B-cell memory response over time in COVID-19 convalescent subjects.
The worldwide spread of coronavirus disease 2019 (COVID-19) highlights the need for assessment of long-term humoral immunity in convalescent subjects. Our objectives were to evaluate long-term IgG antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and B-cell memory response in COVID-19 convalescent subjects. ⋯ The majority of convalescent COVID-19 subjects develop an IgG SARS-CoV-2 antibody response and a protective level prevails over a period of up to 9 months, regardless of age, gender, major blood types or clinical symptomatology.
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Identify factors associated with readmission after an index hospital admission for coronavirus disease 2019 (COVID-19) infection in a single center serving an underserved and predominantly minority population. This retrospective descriptive study included 275 patients who tested COVID-19 positive via reverse transcriptase-polymerase chain reaction assay at our institution and who survived the index hospitalization. The main outcomes were 1- and 6-month readmission rates after an index hospitalization for COVID-19. ⋯ No significant difference was found between inflammatory markers or clinical outcomes during the index hospitalization among patients who were readmitted compared to those who were not. A significant number of patients hospitalized for COVID-19 may be readmitted. The presence of CAD is independently associated with high rates of 6-month readmission.
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The present study was conducted from July 1, 2020 to September 25, 2020 in a dedicated coronavirus disease 2019 (COVID-19) hospital in Delhi, India to provide evidence for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in atmospheric air and surfaces of the hospital wards. Swabs from hospital surfaces (patient's bed, ward floor, and nursing stations area) and suspended particulate matter in ambient air were collected by a portable air sampler from the medicine ward, intensive care unit, and emergency ward admitting COVID-19 patients. ⋯ The presence of the virus in the air beyond a 1-m distance from the patients and surfaces of the hospital indicates that the SARS-CoV-2 virus has the potential to be transmitted by airborne and surface routes from COVID-19 patients to health-care workers working in COVID-19 dedicated hospital. This warrants that precautions against airborne and surface transmission of COVID-19 in the community should be taken when markets, industries, educational institutions, and so on, reopen for normal activities.
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Eur. J. Intern. Med. · Sep 2021
ReviewObesity as an adipose tissue dysfunction disease and a risk factor for infections - Covid-19 as a case study.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV2) disease (COVID-19) is a novel threat that hampers life expectancy especially in obese individuals. Though this association is clinically relevant, the underlying mechanisms are not fully elucidated. ⋯ Further obesity-dependent thoracic mechanical constraints may also incise negatively into the prognosis of obese subjects with COVID-19. This review summarizes the current body of knowledge on the obesity-dependent circumstances triggering an increased risk for COVID-19 severity, and their clinical relevance.