Articles: postoperative.
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Acta Anaesthesiol Scand · Feb 2014
Components of pain assessment after laparoscopic donor nephrectomy.
Pain after laparoscopic surgery can be divided into three components: incisional or superficial wound pain, deep intra-abdominal pain and referred shoulder pain. Better understanding and adequate assessment of post-operative pain may be an important clue to the optimisation of recovery after laparoscopic surgery. Therefore, we performed a components of pain assessment after laparoscopic donor nephrectomy. ⋯ The components of pain assessment revealed that pain related to the Pfannenstiel incision and the deep intra-abdominal pain component are the most important determinants of pain after laparoscopic donor nephrectomy. Further improvement of the management of post-operative pain should focus on these components of pain.
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Cerebral oximetry, though first described for clinical use in cardiac surgery, has been increasingly used in the setting of thoracic surgery. Research focusing on the use of cerebral oximetry in this setting is relatively sparse. This review outlines our current understanding of the use of cerebral oximetry for thoracic surgery. ⋯ Although it is clear that cerebral desaturation can commonly occur during thoracic surgery, it is partly dependent upon how desaturation is defined. The relationship between cerebral desaturation and adverse outcomes after thoracic surgery, as well as the potential ability for cerebral oximetry to guide therapeutic modalities, awaits much needed additional research before being more widely accepted.
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Curr Opin Anaesthesiol · Feb 2014
ReviewUpdate on minimally invasive hemodynamic monitoring in thoracic anesthesia.
Advanced hemodynamic monitoring is indispensable for adequate management of patients undergoing major surgery. This article will summarize minimally invasive hemodynamic monitoring technologies and their potential use in thoracic anesthesia. ⋯ Many different minimally invasive hemodynamic monitoring devices have been developed and clinically introduced in the last years. They offer the advantage of being less invasive and easier to use. However, these techniques have several limitations and data are scarce in patients undergoing thoracic anesthesia, preventing their widespread use so far.
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Curr Opin Anaesthesiol · Feb 2014
ReviewCerebral protection: inflammation, endothelial dysfunction, and postoperative cognitive dysfunction.
Postoperative cognitive dysfunction (POCD) is a well recognized perioperative syndrome, with approximately 15% of patients over the age of 60 years displaying objectively measured decrease in cognitive function as a consequence of anesthesia and surgery. The exact cause, however, remains unknown. This review aims to update anesthesiologists on the recent advancements in the understanding of the pathophysiology of POCD. ⋯ Recent research points to a central role of a neuro-inflammatory cascade in POCD, with endothelial dysfunction potentially aggravating the insult. Investigating the genomic and molecular mechanisms that underlie the intervariation in the inflammatory response to surgery, improving the identification of appropriate endothelial and inflammatory biomarkers, and developing endothelial modulatory and anti-inflammatory (prevention and resolution) strategies are key areas of future translational research. This is important as the elderly, who show increased susceptibility to this and other perioperative illness syndromes, represent an ever-increasing proportion of patients presenting for surgery.
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Observational Study
Accuracy and precision of commonly used methods for quantifying surgery-induced insulin resistance.
Insulin resistance develops in the perioperative setting and has an adverse influence on postoperative recovery and well-being. ⋯ Despite reasonably good linear correlations, the static tests grossly underestimated the degree of insulin resistance that developed in response to surgery.