Articles: spider-bites.
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Randomized Controlled Trial Comparative Study
A randomised controlled trial of intramuscular vs. intravenous antivenom for latrodectism--the RAVE study.
Widow spider-bite causes latrodectism and is associated with significant morbidity worldwide. Antivenom is given by both the intravenous (IV) and intramuscular (IM) routes and it is unclear which is more effective. ⋯ The difference between IV and IM routes of administration of widow spider antivenom is, at best, small and does not justify routinely choosing one route over the other. Furthermore, antivenom may provide no benefit over placebo.
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Annals of Saudi medicine · May 2008
Epidemiological aspects of scorpion stings in Al-Jouf Province, Saudi Arabia.
Information on scorpion stings is available for many parts of Saudi Arabia, but not for Al-Jouf Province. ⋯ Our findings indicate that scorpion stings are common in Al-Jouf Province, especially during the summer. The overall threat to human health was found to be low.
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Br J Clin Pharmacol · Jan 2008
Randomized Controlled Trial Multicenter Study Comparative StudyA comparison of serum antivenom concentrations after intravenous and intramuscular administration of redback (widow) spider antivenom.
There are no studies measuring antivenom concentrations following intramuscular administration. This study aimed to compare antivenom concentrations following intravenous and intramuscular administration of redback spider antivenom (RBSAV). ⋯ RBS AV given by the intramuscular route is unlikely to be effective in the treatment of redback (widow) spider bite.