Articles: outcome-assessment-health-care.
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Randomized Controlled Trial Multicenter Study
Who should have surgery for spinal stenosis? Treatment effect predictors in SPORT.
Combined prospective randomized controlled trial and observational cohort study of spinal stenosis (SpS) with an as-treated analysis. ⋯ With the exception of smokers, patients who met strict inclusion criteria improved more with surgery than with nonoperative treatment, regardless of other specific characteristics. However, TE varied significantly across certain subgroups, and these data can be used to individualize shared decision making discussions about likely outcomes. Smoking cessation should be considered before surgery for SpS.
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Randomized Controlled Trial Multicenter Study
The effect of early initiation of rehabilitation after lumbar spinal fusion: a randomized clinical study.
A multicenter randomized clinical trial including 82 patients. ⋯ Early start of rehabilitation (6 wk vs. 12 wk) after lumbar spinal fusion resulted in inferior outcomes. The improvements in the 12-week group were 4 times better than that in the 6-week group, indicating that the start-up time of rehabilitation is an important contributing factor for the overall outcome.
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Randomized Controlled Trial
Self-management support for moderate-to-severe chronic obstructive pulmonary disease: a pilot randomised controlled trial.
Better self management could improve quality of life (QoL) and reduce hospital admissions in chronic obstructive pulmonary disease (COPD), but the best way to promote it remains unclear. ⋯ This intervention has good potential to meet the UK National Institute for Health and Clinical Excellence criteria for cost effectiveness, and further research is warranted. However, to make a substantial impact on COPD self-management, it will also be necessary to explore other ways to enable patients to access self-management education.
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Psychosomatic medicine · Jul 2012
Randomized Controlled TrialPredictors of cancer-related pain improvement over time.
To determine the predictors of pain improvement among patients being treated for cancer-related pain over 12 months. ⋯ Effective management of depression and comorbid conditions along with improvement of social services could be critical components of a comprehensive pain management. Patients with more severe pain or with recurrent or progressive cancers may require closer monitoring and adequate treatment of pain. Trial Registration clinicaltrials.gov Identifier: NCT00313573.
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Intensive care medicine · May 2012
Randomized Controlled TrialSafety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV®) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study.
IntelliVent-ASV(®) is a development of adaptive support ventilation (ASV) that automatically adjusts ventilation and oxygenation parameters. This study assessed the safety and efficacy of IntelliVent-ASV(®) in sedated intensive care unit (ICU) patients with acute respiratory failure. ⋯ In passive patients with acute respiratory failure, IntelliVent-ASV(®) was safe and able to ventilate patients with less pressure, volume and FiO(2) while producing the same results in terms of oxygenation.