Articles: acetaminophen.
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Comparative Study
A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats.
This study investigated the effects of metamizole and paracetamol on pain and oxidative stress induced by scalpel incision and carrageenan in rats. ⋯ Our results show that metamizole is more effective than paracetamol for treating surgical trauma-related pain, inflammation, and oxidative stress and hence may be a preferential drug to paracetamol.
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African health sciences · Jun 2015
The protective effects of aqueous extract of Carica papaya seeds in paracetamol induced nephrotoxicity in male wistar rats.
Oxidative stress plays a crucial role in the development of drug induced nephrotoxicity. The study aimed to determine the nephroprotective and ameliorative effects of Carica papaya seed extract in paracetamol-induced nephrotoxicity in rats. ⋯ Carica papaya contains nephroprotective phytochemicals and may be useful in preventing kidney damage induced by paracetamol.
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Randomized Controlled Trial Comparative Study
A Randomized, Double-blind, Placebo-Controlled Crossover Trial of Oxymorphone Hydrochloride and Propoxyphene/Acetaminophen Combination for the Treatment of Neurogenic Claudication Associated With Lumbar Spinal Stenosis.
Randomized, double-blind, placebo-controlled, single-dose crossover study. ⋯ 2.