Articles: adrenergic-alpha-antagonists-therapeutic-use.
-
Case Reports Comparative Study
Role of prazosin on cardiovascular manifestations and pulmonary edema following severe scorpion stings in Saudi Arabia.
We report the ameliorating effects of prazosin on the cardiovascular CV manifestations and pulmonary edema PE after treatment with antivenom AV failed to improve the conditions of scorpion stung patients. Three cases of scorpion envenoming, 2 children and one adult, were received at the Accident and Emergency Department of Al-Birk Hospital, Asir Region, Saudi Arabia. ⋯ When polyvalent scorpion PVS AV and intensive supportive treatment failed to show any improvement, prazosin was administered to the patients, which resulted in dramatic improvement in the conditions of the patients. We conclude that PVS AV may not be beneficial in all cases of scorpion envenomation, and prazosin may be an effective alternative for treating scorpion sting cases with CV manifestations and PE.
-
Scand J Urol Nephrol · Jan 2008
Randomized Controlled TrialEfficacy of tamsulosin in medical expulsive therapy for distal ureteral calculi.
To evaluate the potential role of tamsulosin in the medical treatment of distal ureteral stones. ⋯ Our study reveals the efficacy of tamsulosin for the treatment of distal ureteral stones. Tamsulosin should be added to the standard medical approach for treating these stones.
-
Acute renal colic is a common presenting complaint to the emergency department. Recently, medical expulsive therapy using alpha-antagonists or calcium channel blockers has been shown to augment stone passage rates of moderately sized, distal, ureteral stones. Herein is a systematic evaluation of the use of medical expulsive therapy to facilitate ureteral stone expulsion. ⋯ Our results suggest that "medical expulsive therapy," using either alpha-antagonists or calcium channel blockers, augments the stone expulsion rate compared to standard therapy for moderately sized distal ureteral stones.
-
A short cut review was carried out to establish whether tamsulosin enhances the chances of spontaneous stone expulsion in renal colic. Thirty-five papers were found using the reported searches, of which two (a meta-analysis and one further randomised controlled trial) presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are presented in table 3. It is concluded tamsulosin may be useful during periods of watchful waiting to enhance ureteric stone expulsion.
-
Increasingly, men with lower urinary tract symptoms (LUTS) are seeking treatment in the primary care setting. This article reviews the use of alpha-blockers and 5alpha-reductase inhibitors (5ARIs) in the management of LUTS and enlarged prostate. ⋯ NPs play an important role in assessing and treating LUTS in men with enlarged prostate. When treating men with LUTS, assess the severity of symptoms and the extent of prostate enlargement. For symptomatic men with enlarged prostate, long-term therapy with 5ARIs should be considered to treat symptoms as well as address the disease progression.