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Articles: peritoneal-neoplasms-pathology.
Showing all 1 articles tagged:
Peritoneal neoplasms pathology
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The lancet oncology · Jan 2016
Randomized Controlled Trial Multicenter StudyStandard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trial.
Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor, platelet-derived growth factor receptor, and fibroblast growth factor receptor, has shown activity in phase 2 trials in this setting. We investigated the combination of nintedanib with standard carboplatin and paclitaxel chemotherapy in patients with newly diagnosed advanced ovarian cancer. ⋯ Boehringer Ingelheim.