Articles: pain.
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In the Thermal Grill Illusion (TGI), the spatial alternation of non-noxious warm and cool temperatures elicits burning sensations that resemble the presence of noxious stimuli. Previous research has largely relied on the use of specific temperature values (i.e., 20 °C and 40 °C) to study this phenomenon in both healthy individuals and patient populations. However, this methodology fails to account for inter-individual differences in thermal sensitivity, limiting the precision with which TGI responses can be evaluated across diverse populations. ⋯ The 2D-TGC offers a comprehensive approach to investigate the TGI across populations with altered thermal sensitivity, and can be integrated with other methods (e.g., neuroimaging) to elucidate the mechanisms responsible for perceptual illusions in the thermo-nociceptive system. PERSPECTIVE: This study reveals that the Thermal Grill Illusion can be accurately measured using psychophysical methods. The innovative Two-Dimensional Thermal Grill Calibration protocol allows for personalized temperature assessments, enhancing our understanding of thermal sensitivity variations and perceptual illusions in the thermo-nociceptive system across different populations.
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The aim of the study was to examine the hotspots and global trends of massage in nursing research. ⋯ The results of the study show that massage research is particularly prominent in certain medical fields such as cancer and that studies on the effects of massage in these fields are important. Furthermore, the fact that the leading authors of massage research are often specialized in specific fields and that there is limited collaboration between authors plays an important role in determining the future directions of massage research and highlights the need to encourage interdisciplinary collaboration.
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Burns can cause patients significant pain at the time of injury and during subsequent treatment. Other people's pain often elicits empathic responses in observers. However, effective emotion regulation strategies are needed to manage personal distress, which may otherwise inhibit helping behaviour. ⋯ Burns nurses' attempts at regulating their emotions were influenced by their beliefs about what makes a 'good' nurse. Gross's model of emotion regulation provides a useful framework for understanding these strategies, but further research is needed into the helpfulness thereof for nurses and patients.
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Emerging evidence indicates that cyclic nucleotide phosphodiesterases exert distinct functions in pain processing and that targeting phosphodiesterases might be a novel strategy for pain relief. This study hypothesized that the phosphodiesterase isoform phosphodiesterase 10A (PDE10A) might be a target for analgesic therapy. ⋯ Collectively, the data support the idea that PDE10A is a suitable target for the development of efficacious analgesic drugs.