Articles: pain.
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Multicenter Study
Pain control in Taiwanese patients with cancer: a multicenter, patient-oriented survey.
Under-treatment of cancer pain remains a common problem in Taiwan. Prior studies were mainly in hospitalized patients and limited to one or a few centers. This prospective, multicenter, patient-focused survey assessed the prevalence, severity and management of cancer pain in oncology clinic outpatients. Analgesic use and patient satisfaction with analgesic therapy were also evaluated. ⋯ The results of this survey of Taiwanese outpatients with cancer confirm that cancer pain is under-treated in oncology clinics in Taiwan. A major goal of cancer management is to achieve high rates of patient satisfaction and compliance with treatment which maintains or improves quality of life.
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J Pain Symptom Manage · Dec 2005
Multicenter Study Comparative Study Clinical TrialMeasuring pain intensity in nursing home residents.
Assessing pain intensity in nursing home residents remains a challenge. As part of a multifaceted intervention study to improve pain practices in nursing homes, quarterly pain assessments were conducted in 12 Colorado nursing homes. Residents who reported pain or discomfort of any kind in the past 24 hours were asked to choose one of three pain intensity scales to quantify their current and highest level of pain intensity. ⋯ More than one-half of residents reporting pain had an observable pain indicator. There was a monotonic relationship between reported pain intensity and number of observed pain indicators. To improve pain assessment and management in nursing homes, residents should be given a choice of pain intensity scales and observed for possible pain behaviors.
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The Journal of urology · Dec 2005
Randomized Controlled Trial Multicenter StudyGynecomastia and breast pain induced by adjuvant therapy with bicalutamide after radical prostatectomy in patients with prostate cancer: the role of tamoxifen and radiotherapy.
We investigated the role of tamoxifen and radiotherapy (RT) for the prevention and treatment of gynecomastia and breast pain during adjuvant bicalutamide monotherapy after radical prostatectomy (RP) in patients with prostate cancer. Also, we evaluated their effects on patient hormonal status, quality of life (QOL), sexual function and prostate specific antigen relapse-free survival. ⋯ Gynecomastia and breast pain induced by bicalutamide monotherapy after RP can be prevented and treated. Tamoxifen has been shown to be more effective and safe than RT in this setting. QOL and sexual function are not negatively influenced by these 2 treatment options.
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Arch Phys Med Rehabil · Dec 2005
Randomized Controlled Trial Multicenter StudyEfficacy and safety of oxymorphone immediate release for the treatment of mild to moderate pain after ambulatory orthopedic surgery: results of a randomized, double-blind, placebo-controlled trial.
To assess the analgesic efficacy and safety of 5 mg of oxymorphone immediate release (IR) for mild to moderate pain. ⋯ Five milligrams of oxymorphone IR was well tolerated and effective at relieving mild or moderate postsurgical pain after outpatient knee surgery.
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Randomized Controlled Trial Multicenter Study
Tramadol/acetaminophen tablets in the treatment of postsurgical orthopedic pain.
Tramadol/acetaminophen (APAP) combination tablets were shown effective and safe for postsurgical orthopedic pain in a 6-day, multicenter, randomized, double-blind, active- and placebo-controlled study. Of 305 intent-to-treat (ITT) postsurgical patients, 153 patients undergoing arthroscopy who had at least moderate pain were randomized to receive either tramadol 37.5 mg/APAP 325 mg (mean, 4.3 tablets), or codeine 30 mg/APAP 300 mg (mean, 4.6 tablets), or placebo. Tramadol/APAP was superior to placebo for the following outcome variables: total pain relief (TOTPAR, P = .013), sum of pain intensity differences (SPID, P = .049), sum of total pain relief and sum of pain intensity differences (SPRID, P = .018), and average daily pain relief (P = .031). Similar incidence of adverse events for tramadol/APAP and codeine/APAP was found, except for constipation (0% vs 10.9%) and vomiting (8.2% vs 16.4%).