Articles: pain.
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Comparative Study
Infusion analgesia for acute war injuries. A comparison of pentazocine and ketamine.
Continuous intravenous infusions of ketamine and pentazocine have been used to provide analgesia in 18 patients with acute war injuries. The drugs were given alternately. ⋯ Arterial blood pressure and respiratory rate were maintained following ketamine but tended to fall after pentazocine. It is suggested that ketamine would be the better agent in patients with hypovolaemia or respiratory depression.
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We treated 72 patients, referred to a pain clinic for acute herpes zoster neuralgia, with local anesthetics administered by nerve block and infiltration. Only those patients with severe pain initially proved to be at risk for the development of chronic postherpetic neuralgia (defined as pain in the involved dermatomes lasting at least six months). Although local anesthetic injections effectively relieved the acute pain of active herpes zoster, they did not prevent the development of chronic postherpetic neuralgia.
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Vestn. Khir. Im. I. I. Grek. · Jun 1984
Comparative Study[Postoperative peridural analgesia with morphine, fentanyl and dipidolor].
The experience with peridural analgesia used in the postoperative period in 183 patients has shown advantages of morphine, phentanyl and dipydolor over routine methods of analgesia. The peridural injection of the drugs mentioned has been shown to give a longer analgetic effect than local anesthetics, to facilitate stabilization of hemodynamics in the postoperative period.
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Clinical Trial Controlled Clinical Trial
Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone.
The effects of intense exercise on pain perception, mood, and plasma endocrine levels in man were studied under naloxone and saline conditions. Twelve long-distance runners (mean weekly mileage = 41.5) were evaluated on thermal, ischemic, and cold pressor pain tests and on mood visual analogue scales (VAS). Blood was drawn for determination of plasma levels of beta-endorphin-like immunoreactivity (BEir), growth hormone (GH), adrenocorticotrophic hormone (ACTH), and prolactin (PRL). ⋯ Plasma levels of BEir, ACTH, GH, and PRL were significantly increased post-run. The results show that long-distance running produces hypoalgesia and mood elevation in man. The effects of naloxone implicate endogenous opioid neural systems as mechanisms of some but not all of the run-induced alterations in mood and pain perception.