Articles: apnea-diagnosis.
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Clinical Trial
An evaluation of capnography monitoring during the apnoea test in brain-dead patients.
Diagnosis of brain death usually requires the absence of spontaneous respiratory movements during the apnoea test and an arterial carbon dioxide partial pressure above 60 mmHg. On the other hand, although capnography (end-tidal CO(2)) is currently monitored in intensive care unit patients, it has not been evaluated during the apnoea test in brain-dead patients. Therefore, the aim of this prospective study was first to investigate the usefulness of capnography monitoring, and secondly to evaluate the variation of the carbon dioxide partial pressure-end-tidal CO(2) gradient during the apnoea test in clinically brain-dead patients. ⋯ End-tidal CO(2) should be systematically monitored and recorded, at least for medico-legal considerations, during the apnoea test in brain-dead patients. The high variability in the carbon dioxide partial pressure-end-tidal CO(2) gradient increase precludes any extrapolation of the carbon dioxide partial pressure from the end-tidal CO(2) at the end of the apnoea test.
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Curr. Opin. Pediatr. · Jun 2007
ReviewAn update on the approach to apparent life-threatening events.
Apparent life-threatening events are an ongoing diagnostic dilemma for clinicians. Since most apparent life-threatening event episodes occur in infants under 6 months of age, they can generate considerable anxiety in parents and providers. This review will discuss issues to consider in the evaluation of infants after an apparent life-threatening event. To ensure proper management, a systematic approach should be taken to attempt to determine the cause of the event. ⋯ After a careful review of the literature, prone sleeping is one of the biggest risk factors for sudden infant death syndrome. The association between apparent life-threatening events and sudden infant death syndrome remains to be explored further, but current evidence suggests minimal risk after an apparent life-threatening event episode. This article will help clinicians prepare for this difficult challenge by providing up-to-date information and identifying problems to be addressed in future research.
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Tohoku J. Exp. Med. · Feb 2007
Comparative StudyThe safe limits of mechanical factors in the apnea testing for the diagnosis of brain death.
Apneic oxygenation is an apnea testing method in the diagnosis of brain death. In this method, oxygen (O2) is delivered into the trachea via an O2 catheter (O2C). However, barotrauma may develop during O2 insufflation into the trachea. ⋯ The pressure was significantly higher at the flow rate of 10 L min(-1) O2 compared with the flow rate of 6 L min(-1) O2 (p < 0.01). Thus, ETT/O2C ratio, O2C tip position in ETT and O2 flow rate are the important factors that determine the airway pressure in the trachea during O2 insufflation. In conclusion, overlooked mechanical factors dangerously increase airway pressure during apnea testing.