Articles: anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
Anaesthesia for surgical correction of fractured femoral neck. A comparison of three techniques.
Sixty patients with fractured neck of femur and scheduled for surgical correction were randomly allocated to receive one of three anaesthetic techniques: general anaesthesia; spinal analgesia; psoas compartment block. The patients in the local anaesthetic groups also received a light general anaesthetic. There was little difference in the pre-, intra- and postoperative events, and no difference in postoperative mortality.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effects of concentration of local anaesthetic drugs in extradural block.
An increase in the concentration of bupivacaine from 0.5% to 0.75% and etidocaine from 1.0% to 1.5% for extradural block resulted in a more rapid onset of sensory analgesia and motor blockade, a greater frequency of adequate analgesia,a greater depth of motor block and a longer duration of sensory analgesia and motor blockade. An increase in the concentration of prilocaine from 2% to 3% failed to reveal any significant advantage. The use of the more concentrated solutions of bupivacaine and etidocaine would appear to afford significant clinical advantages in extradural anaesthesia for surgery.
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Anesthesia and analgesia · Oct 1980
Randomized Controlled Trial Comparative Study Clinical TrialSpinal anesthesia: bupivacaine compared with tetracaine.
A solution of 0.75% bupivacaine (Marcaine) in 8.25% dextrose was compared with a similar solution of tetracaine (Pontocaine), the drug most used for spinal anesthesia in the USA. The study employed a randomized double-blind method and a standardized technique for spinal anesthesia in 435 patients. For perineal and lower extremity surgery, 7.5 mg of the local anesthetic was injected, and for intra-abdominal gynecologic surgery, 12 mg was administered. ⋯ Epinephrine added to the local anesthetic solution significantly increased the duration of action of both drugs. It also prolonged the duration of postoperative analgesia of tetracaine significantly more than the duration of bupivacaine. Bupivacaine 0.75% in 8.25% dextrose is a safe, reliable local anesthetic solution for spinal anesthesia.
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Randomized Controlled Trial Comparative Study Clinical Trial
Anaesthesia for transurethral prostatectomy. A comparison of spinal intradural analgesia with two methods of general anaesthesia.
One hundred and fifty patients who presented for transurethral prostatectomy were randomly allocated to one of three groups for the purpose of anaesthesia. Group A received spinal intradural analgesia, Group B general anaesthesia with spontaneous ventilation and Group C general anaesthesia with controlled ventilation. The comparability of the three groups was established. ⋯ Dysrhythmias were significantly higher in Group B. The results support the conclusion that the methods of choice for anaesthesia for transurethral prostatectomy are spinal analgesia or general anaesthesia using muscle relaxants and controlled ventilation. The final decision is a matter of personal preference.
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Anesthesia and analgesia · Sep 1980
Randomized Controlled Trial Comparative Study Clinical TrialThiopental-nitrous oxide- halothane anesthesia and repeated succinylcholine: comparison of preoperative glycopyrrolate and atropine administration.
The effects of glycopyrrolate and atropine given prior to thiopental-N2O-halothane anesthesia on bradyarrhythmias associated with the administration of succinylcholine were studied and compared. Sixty healthy adult patients were allocated at random to one of three groups. ⋯ ECG monitoring was continuous, and serum K+ levels as well as PaO2 and paCO2 were repeatedly measured. In all three groups patients were adequately and equally protected against serious bradyarrhythmias following the second dose of succinylcholine by atropine and glycopyrrolate in the doses used.