Articles: closed-circuit-anesthesia.
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Acta Anaesthesiol. Sin. · Jun 2003
Randomized Controlled Trial Comparative Study Clinical TrialClosed-circuit anesthesia prolongs the neuromuscular blockade of rocuronium.
Volatile anesthetics are known to potentiate the neuromuscular blocking effect of nondepolarizing muscle relaxants. The influences of anesthetic techniques, closed-circuit anesthesia (CCA) and high flow semi-closed anesthesia (SCA), on the neuromuscular blockade of rocuronium has not yet been studied in detail. This study was purposed to compare the effects of isoflurane conveyed in minimal flow (CCA) and in high flow (SCA) on the neuromuscular blockade of rocuronium. ⋯ We conclude that CCA may further prolong the neuromuscular blocking effect of rocuronium than SCA.
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The large number of anaesthetics administered means that the total cost to a hospital of inhalational anaesthetic agent such as isoflurane or sevoflurane can be considerable. The total anaesthetic gas flow is a major determinant of the use of these agents. Modern anaesthetic machines and monitoring facilitate reduced gas flows, which can significantly reduce wastage of these anaesthetic agents. The purpose of this study was to audit gas flow rates and volatile anaesthetic use. ⋯ Given the low flows used, the small difference between study periods was not surprising. The gas flows recorded represent responsible use of anaesthetic agents and are at least as good as flows achieved in previous studies that employed various methods to encourage their reduction.