Articles: critical-illness.
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Randomized Controlled Trial Multicenter Study Comparative Study
The ADRENAL study protocol: adjunctive corticosteroid treatment in critically ill patients with septic shock.
There is considerable global uncertainty on the role of low-dose corticosteroids in septic shock, which translates into variations in prescribing practices. ⋯ The run-in phase has been completed and the main trial commenced in February 2013. The trial should generate results that will inform and influence prescribing of corticosteroids in septic shock.
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Randomized Controlled Trial
Airflow distribution with manual hyperinflation as assessed through gamma camera imaging: a crossover randomised trial.
Manual hyperinflation (MHI) has been shown to improve lung compliance, reduce airway resistance, and enhance secretion removal and peak expiratory flow. The aims of this study were to investigate whether there is a difference in airflow distribution through patients' lungs when using the Laerdal and Mapleson-C circuits at a set level of positive end-expiratory pressure (PEEP), and to establish whether differences in lung compliance and haemodynamic status exist when patients are treated with both these MHI circuits. ⋯ Airflow distribution through patients' lungs was similar when the Laerdal and Mapleson-C MHI circuits were compared using a set level of PEEP in the supine position.
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Randomized Controlled Trial Multicenter Study
0.9 % saline vs 6 % HES 130/0.4 for fluid resuscitation in critically ill patients.
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Journal of critical care · Jun 2013
Randomized Controlled TrialAssessment of the safety and feasibility of administering antipyretic therapy in critically ill adults: a pilot randomized clinical trial.
To assess the safety and feasibility of treating critically ill adults with different fever control strategies. ⋯ This study demonstrated the safety and feasibility of administering antipyretic therapy in critically ill adults. The key finding was a lower than expected incidence of fever.
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Randomized Controlled Trial
Near-infrared light device can improve intravenous cannulation in critically ill children.
Vascular access in critically ill children can be a real challenge for medical staff. ⋯ The use of a near-infrared light vein-viewing device for vascular access in critically ill children can decrease the total medical time and cost.