Articles: anesthetics.
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Reg Anesth Pain Med · Jul 2011
Multicenter Study Comparative StudySpinal anesthesia failure after local anesthetic injection into cerebrospinal fluid: a multicenter prospective analysis of its incidence and related risk factors in 1214 patients.
Different mechanisms have been proposed to explain spinal anesthesia failure even after LA injection into the subarachnoid space. The aim of this prospective multicenter study was to assess the incidence of spinal anesthesia failure, excluding technical problems, and then to suggest independent factors leading to failure. ⋯ The results of this study showed that the incidence of spinal anesthesia failure was 3.2%. The number of puncture attempts at 3 or more and the absence of adjuvant medication associated with local anesthetic were independent factors associated with the increased risk of failure. The failure of spinal anesthesia was rare in patients older than 70 years.
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Multicenter Study
Effect of patient sex on general anaesthesia and recovery.
Numerous studies have shown that women emerge faster from general anaesthesia than men, and differ in their postoperative recovery profile. The extent and underlying mechanisms for these sex-related differences in general anaesthesia are unclear. ⋯ Patient sex is an independent factor influencing the response to anaesthesia and recovery after surgery. Women emerged faster from general anaesthesia but their overall quality of recovery was poorer. Female sex hormones, particularly progesterone, might be involved, with premenopausal women having faster recovery time but poor overall recovery.
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Randomized Controlled Trial Multicenter Study Comparative Study
Morbidity related to emergency endotracheal intubation--a substudy of the KETAmine SEDation trial.
To evaluate the association between emergency tracheal intubation difficulty and the occurrence of immediate complications and mortality, when standardised airway management is performed by emergency physicians. ⋯ Difficult intubation, measured by the IDS score, is associated with increased morbidity and mortality in patients managed under emergent conditions.
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Multicenter Study Comparative Study
Errors in drug administration by anaesthetists in public hospitals in the Free State.
To investigate errors in administering drugs by anaesthetists working in public hospitals in the Free State province. ⋯ The response rate was 46.3%; 48.8% were medical officers, and 39.3% of participants were involved in at least one event of erroneous drug administration. Registrars and specialists reported the most errors. Most events were of no clinical significance, caused no permanent harm to patients, and most commonly involved fentanyl and suxamethonium. Of the respondents, 23.8% indicated that they were aware of a South African standard for colour-coding syringe labels, and 92.9% indicated that they would report anaesthetic errors if a single reporting agency for such events existed. CONCLUSIONS. More than a third of participating anaesthetists were involved in a drug error at some stage in their practice. Preventive systems and precautionary measures should be put in place to reduce drug administration errors.
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Gastrointest. Endosc. · Apr 2011
Randomized Controlled Trial Multicenter Study Comparative StudyComputer-assisted personalized sedation for upper endoscopy and colonoscopy: a comparative, multicenter randomized study.
The SEDASYS System is an investigational computer-assisted personalized sedation system integrating propofol delivery with patient monitoring to enable endoscopist/nurse teams to safely administer propofol. ⋯ The SEDASYS System could provide endoscopist/nurse teams a safe and effective on-label means to administer propofol to effect minimal to moderate sedation during routine colonoscopy and EGD.