Articles: anesthetics.
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A total of 2,511 patients who received spinal anesthesia for cesarean delivery were observed for the development of postdural puncture headache (PDPH); 804 patients received a mixture of tetracaine and procaine, 942 received bupivacaine-glucose, and 765 received lidocaine-glucose. They were observed for the development of PDPH for a minimum of 72 h. ⋯ The differences between all groups was statistically significant. No differences were found in the percentage of patients who ultimately required epidural blood patch for relief of symptoms after 36 h.
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Pediatric regional anesthesia has been viewed less favorably in the past because it was often considered an extra and unnecessary procedure. Current anesthesia practice demonstrates that local anesthetic techniques are of great value either as the sole anesthetic or for postoperative analgesia in the pediatric population. ⋯ The advantages and special considerations of the pediatric population also are reviewed. Regional anesthesia in the pediatric patient population does have its benefits and should be considered as an option in the provision of anesthesia in the pediatric age group.
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Anesthesia and analgesia · Mar 1990
Comparative StudyPharmacokinetics of ropivacaine in nonpregnant and pregnant ewes.
The pharmacokinetics of ropivacaine were studied in chronically instrumented nonpregnant and pregnant ewes. On the day of study, the urinary bladder was catheterized. Ropivacaine (2.5 or 3.0 mg/kg) was administered by intravenous infusion over 2 or 4 min. ⋯ It is concluded that ovine pregnancy is accompanied by changes in the pharmacokinetics of ropivacaine. Inadvertent intravenous injections of similar drug doses to pregnant and nonpregnant women might result in higher plasma concentrations of ropivacaine in the former. However, the rate of decline in plasma levels of the drug would be similar in both.