Articles: blood-glucose-analysis.
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Randomized Controlled Trial
The effect of perioperative glucose control on postoperative insulin resistance.
Postoperative insulin resistance and the consequent hyperglycemia affects clinical outcome. Insulin sensitivity may be modulated by preoperative nutrition, adequate pain management and minimal invasive surgery. This study aims to disclose the impact of perioperative glucose control on postoperative insulin resistance. ⋯ This trial revealed a significant difference in postoperative insulin resistance in the group treated with insulin during surgery.
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Anesthesia and analgesia · Sep 2012
Randomized Controlled TrialA novel computerized fading memory algorithm for glycemic control in postoperative surgical patients.
Hyperglycemia is commonly encountered in critically ill patients and is associated with increased mortality and morbidity. To better control blood glucose levels, we previously developed a new computerized fading memory (FM) algorithm. In this study we evaluated the safety and efficacy of this algorithm in surgical intensive care unit (SICU) patients and compared its performance against the existing insulin-infusion algorithm (named VA algorithm) used in our institution. ⋯ The novel computerized FM algorithm for glycemic control, which emulates physiologic biphasic insulin secretion, managed glucose better than the existing algorithm without any episodes of hypoglycemia. The FM algorithm had less glycemic variability and used less insulin when compared to the conventional clinical algorithm.
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Randomized Controlled Trial
Biophysiologic outcomes of the Enhancing Adherence in Type 2 Diabetes (ENHANCE) trial.
Behavioral research to improve lifestyle in broadly defined populations of patients with type 2 diabetes is limited. ⋯ Two behavioral approaches to improving general lifestyle management in individuals with type 2 diabetes mellitus were effective in improving glycemic control, but no significant between-group differences were observed.
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Randomized Controlled Trial
Nurse- vs nomogram-directed glucose control in a cardiovascular intensive care unit.
Paper-based nomograms are reasonably effective for achieving glycemic control but have low adherence and are less adaptive than nurses' judgment. ⋯ In an intensive care unit where nurses generally accepted the need for tight glucose control, nurse-directed control was as effective and as safe as nomogram-based control.
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Intensive care medicine · Apr 2012
Randomized Controlled TrialDyslipidemia: a prospective controlled randomized trial of intensive glycemic control in sepsis.
Metabolic disturbances are quite common in critically ill patients. Glycemic control appears to be an important adjuvant therapy in such patients. In addition, disorders of lipid metabolism are associated with worse prognoses. The purpose of this study was to investigate the effects that two different glycemic control protocols have on lipid profile and metabolism. ⋯ Free fatty acids respond to intensive glycemic control and, because of their high toxicity, can be a therapeutic target in patients with sepsis.