Articles: ventilators.
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Randomized Controlled Trial
Reversal of propofol-induced depression of the hypoxic ventilatory response by BK-channel blocker ENA-001: a randomized controlled trial.
The agnostic respiratory stimulant ENA-001 blocks carotid body BK-channels, reversing propofol's impairment of the hypoxic ventilatory response.
pearl -
Critical care medicine · Jun 2024
Randomized Controlled TrialEarly Mobilization Using a Mobile Patient Lift in the ICU: A Randomized Controlled Trial.
To ascertain whether a mobile patient lift facilitates early mobilization in ventilated ICU patients. ⋯ The use of mobile patient lifts facilitates the earlier standing of patients on ventilators. This may contribute to patients improved physical function in the ICU.
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Lung protective ventilation is considered standard of care in the intensive care unit. However, modifying the ventilator settings can be challenging and is time consuming. Closed loop modes of ventilation are increasingly attractive for use in critically ill patients. With closed loop ventilation, settings that are typically managed by the ICU professionals are under control of the ventilator's algorithms. ⋯ Closed loop ventilation modes are at least as effective in choosing correct ventilator settings as ventilation performed by ICU professionals and have the potential to reduce the workload related to ventilation. Nevertheless, there is a lack of sufficient research to comprehensively assess the overall impact of these modes on patient outcomes, and on the workload of ICU staff.