• J Coll Physicians Surg Pak · Feb 2021

    Association of Early-onset Androgenetic Alopecia and Metabolic Syndrome.

    • Fatima Zia Sheikh, Ghazala Butt, Rukhsha Hafeez, Aiman Maqsood, Faria Altaf, and Ijaz Hussain.
    • Departement of Dermatology, King Edward Medical University/Mayo Hospital, Lahore, Pakistan.
    • J Coll Physicians Surg Pak. 2021 Feb 1; 31 (2): 123-127.

    Objective To evaluate the association of early-onset AGA (androgenetic alopecia) and metabolic syndrome in the younger male population.Study DesignCase-control study.Place And Duration Of Study Department of Dermatology, Mayo Hospital Lahore, from October 2017 to March 2018.MethodologyA total of 202 patients were enrolled, 101 male patients with early-onset AGA (cases with a alopecia between 20-36 years of age), and were matched with 101 controls. All measurements regarding BMI, metabolic syndrome, and grades of alopecia were recorded on a pre-designed proforma.ResultsOf the 101 cases (mean age 27.77 ± 5.04 years), 27 (26.7%) had grade 3, 41 (40.6%) had grade 4, 29 (28.7%) had grade 5 and 4 (4%) had grade 6 AGA. Patients of AGA had an approximate four times increased frequency of metabolic syndrome. Of the cases 12 (11.9%) had metabolic syndrome whereas it was found in 3 (3%) of the control group. A significant association was found between cases of AGA and metabolic syndrome (p=0.016).ConclusionThis study suggests a significant association of AGA with metabolic syndrome. Key Words: Androgenetic alopecia, Metabolic syndrome, Early-onset alopecia, Cardiovascular disease.

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