• Sergio Aguilar-Gaxiola, Gustavo Loera, Estella M Geraghty, Hendry Ton, Lim Carmen C W CCW University of California Davis, School of Medicine, 2921 Stockton Boulevard, Suite 1400, Sacramento, CA 95817, United States., Peter de Jonge, Ronald C Kessler, José Posada-Villa, María Elena Medina-Mora, Chiyi Hu, Fabian Fiestas, Ronny Bruffaerts, Viviane Kovess-Masféty, Ali Obaid Al-Hamzawi, Daphna Levinson, Giovanni de Girolamo, Yoshibumi Nakane, Margreet Ten Have, Siobhan O'Neill, Bogdan Wojtyniak, José Miguel Caldas de Almeida, Silvia Florescu, Josep Maria Haro, and Kate M Scott.
• University of California Davis, School of Medicine, 2921 Stockton Boulevard, Suite 1400, Sacramento, CA 95817, United States. Electronic address: aguilargaxiola@ucdavis.edu.
• J Psychosom Res. 2016 Mar 1; 82: 11-16.

ObjectiveWe investigated the associations between DSM-IV mental disorders and subsequent arthritis onset, with and without mental disorder comorbidity adjustment. We aimed to determine whether specific types of mental disorders and increasing numbers of mental disorders were associated with the onset of arthritis later in life.MethodData were collected using face-to-face household surveys, conducted in 19 countries from different regions of the world (n=52,095). Lifetime prevalence and age at onset of 16 DSM-IV mental disorders were assessed retrospectively with the World Health Organization (WHO) Composite International Diagnostic Interview (WHO-CIDI). Arthritis was assessed by self-report of lifetime history of arthritis and age at onset. Survival analyses estimated the association of initial onset of mental disorders with subsequent onset of arthritis.ResultsAfter adjusting for comorbidity, the number of mood, anxiety, impulse-control, and substance disorders remained significantly associated with arthritis onset showing odds ratios (ORs) ranging from 1.2 to 1.4. Additionally, the risk of developing arthritis increased as the number of mental disorders increased from one to five or more disorders.ConclusionThis study suggests links between mental disorders and subsequent arthritis onset using a large, multi-country dataset. These associations lend support to the idea that it may be possible to reduce the severity of mental disorder-arthritis comorbidity through early identification and effective treatment of mental disorders.Copyright © 2016 Elsevier Inc. All rights reserved.

34 keywords...

hide…