• The Ochsner journal · Jan 2013

    Case Reports

    Dexmedetomidine for anterior mediastinal mass computed tomography-guided biopsy: a case series.

    • Dominic S Carollo, Sophie Pestieau, and Richard Bosco.
    • Department of Anesthesiology and Pain Management, Ochsner Clinic Foundation, New Orleans, LA.
    • Ochsner J. 2013 Jan 1; 13 (4): 541-3.

    BackgroundSedation of children undergoing biopsies of anterior mediastinal masses can be challenging because of the absolute necessity of ensuring minimal smooth muscle relaxation and preventing airway collapse. Furthermore, positive pressure ventilation may be difficult or impossible and may also pose the additional risks of hemodynamic compromise in the pediatric patient.Case ReportsWe present a case series of 3 children who were successfully sedated for computed tomography (CT)-guided mediastinal biopsies with dexmedetomidine.ConclusionDexmedetomidine, a selective alpha-2 adrenoreceptor agonist that maintains the smooth musculature of the pediatric airway, provides the ability to sustain spontaneous ventilation in patients with airway compression. Dexmedetomidine is a safe, reliable anesthetic for biopsy of children with anterior mediastinal masses.

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