• Journal of anesthesia · Jan 2004

    Case Reports

    Conversion of atrial fibrillation to sinus rhythm during landiolol infusion.

    • Taku Mayahara, Maria Goto, Mikako Sato, Takeshi Kanazawa, Shinji Isomine, Hiroshi Nakajima, and Koji Sakaida.
    • Department of Anesthesiology and Critical Care Medicine, Funabashi Municipal Medical Center, Funabashi, Japan.
    • J Anesth. 2004 Jan 1; 18 (4): 304-6.

    AbstractA 71-year-old woman with a history of persistent atrial fibrillation underwent clipping of a ruptured cerebral artery aneurysm. During the surgery her cardiac rhythm was atrial fibrillation and the ventricular rate increased to 130 beats.min(-1). Administration of landiolol was started with 1-min loading infusion at 0.125 mg.kg(-1).min(-1) and continuous infusion at 0.04 mg.kg(-1).min(-1), which was effective in controlling the ventricular rate without causing hypotension. Approximately 120 min after the landiolol infusion was started, the atrial fibrillation was converted to sinus rhythm. Her sinus rhythm was maintained until she left the operating room, even after discontinuation of landiolol.

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