• A-Y Oh, K-S Seo, S-D Kim, C-S Kim, and H-S Kim.
• Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul 110-744, Korea.
• Acta Anaesthesiol Scand. 2005 Mar 1;49(3):297-9.

BackgroundEmergence agitation (EA) is more frequent after sevoflurane anesthesia than other inhalational agents but the etiology remains unclear. We investigated whether the EA after sevoflurane anesthesia is related to rapid emergence.MethodsEighty-five patients, aged 1-7 years, undergoing elective urology surgery were studied. After induction, anesthesia was maintained with 2.0-2.5% sevoflurane and 50% N(2)O. BIS was monitored continuously throughout surgery and emergence. At the end of surgery, the children were randomly assigned to one of two groups: group I, immediate cessation of sevoflurane; or group G, gradual decrease of sevoflurane with the rate of 0.1%.min(-1). Emergence agitation score was recorded during recovery.ResultsTimes from immediate cessation or start of decrease of sevoflurane to BIS 70, 80, 90 and extubation were significantly longer in group G. The incidence of severe agitation (score > or =3) was not significantly different between group I and group G: which were 35.7% and 32.6%, respectively.ConclusionProlonged recovery did not reduce the incidence of EA following sevoflurane anesthesia in children.

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