• Acta clinica Croatica · Jun 2021

    Case Reports

    CONCURRENT DEEP VEIN THROMBOSIS AND PULMONARY EMBOLISM ASSOCIATED WITH HYPERTHYROIDISM: A CASE REPORT.

    • Josip Katić, Ana Katić, Karla Katić, Darko Duplančić, and Mislav Lozo.
    • 1Department of Cardiology, Split University Hospital Centre, Split, Croatia; 2University of Split School of Medicine, Split, Croatia; 3Department of Ophthalmology, Split University Hospital Centre, Split, Croatia.
    • Acta Clin Croat. 2021 Jun 1; 60 (2): 314-316.

    AbstractNumerous disorders of coagulation and fibrinolysis have been reported in patients with thyroid diseases, especially with hyperthyroidism. Most articles are focused on deep vein thrombosis risk, however, few of them describe association between hyperthyroidism and pulmonary embolism. We report a case of a 43-year-old woman with long-term uncontrolled hyperthyroidism complicated by venous thromboembolism. The potential mechanisms could be endothelial dysfunction, decreased fibrinolytic activity, and increased levels of coagulation factors. Thyroid evaluation should be recommended in patients with unprovoked venous thromboembolic events.

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