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- Amirhossein Ahmadi, Juan D Gispert, Arcadi Navarro, Natalia Vilor-Tejedor, and Iman Sadeghi.
- Department of Biology, Faculty of Nano and BioScience and Technology, Persian Gulf University, Bushehr 75169, Iran.
- Neuroscience. 2021 Dec 15; 479: 192-205.
AbstractIn recent decades, our understanding of the molecular changes involved in neurodegenerative diseases has been transformed. Single-cell RNA sequencing and single-nucleus RNA sequencing technologies have been applied to provide cellular and molecular details of the brain at the single-cell level. This has expanded our knowledge of the central nervous system and provided insights into the molecular vulnerability of brain cell types and underlying mechanisms in neurodegenerative diseases. In this review, we highlight the recent advances and findings related to neurodegenerative diseases using these cutting-edge technologies.Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.
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