• Tryggve Lundar, Bernt Johan Due-Tønnessen, Radek Frič, Petter Brandal, and Paulina Due-Tønnessen.
• Department of Neurosurgery, Oslo University Hospital, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address: tryggve.lundar@gmail.com.
• World Neurosurg. 2022 Feb 1; 158: e810-e819.

ObjectiveTo present long-term follow-up of a consecutive single-institutional series of patients treated for choroid plexus tumors over 8 decades.MethodsFrom 1939 to 2020, 59 children were treated for choroid plexus tumors. Median age at diagnosis was 1.7 years.ResultsGross total resection was achieved in 51 patients (86%). Ten patients (17%) underwent >1 resection. During the first 4 decades of the study (1939-1979), 14 patients with plexus papillomas were treated. Operative mortality was 50%, with 6 of the remaining 7 patients experiencing excellent survival with follow-up periods of 41-81 years. In the last 4 decades (1980-2020), 38 patients had low-grade tumors, and all were alive at the latest follow-up (range, 0.5-39 years). Observed 5-year survival in this subgroup was 100% (n = 30), as was observed 10-year survival (n = 26). One of 7 (14%) patients with atypical choroid plexus papilloma and 3 of 31 patients (10%) with choroid plexus papilloma underwent a second resection owing to recurrent tumor. At last follow-up, 47 patients (80%) were alive; 45 (96%) had a Barthel Index score of 100 and 2 had a Barthel Index score of 50. Today 25 patients are adults (20-59 years old); 17 work full-time, 4 work part-time, and 4 are unable to work.ConclusionsLow-grade choroid plexus tumors can be cured with gross total resection alone, with excellent long-term survival and functionality. The vast majority of survivors live independently as adults and work full-time. Recurrences are uncommon (8.7%), appear within the first few years after primary surgery, and can be treated with repeat resections.Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

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