• Yan-Ling Wang, Qi Hua, Cheng-Rui Bai, and Qing Tang.
• Department of Cardiology, Xuanwu Hospital, Capital Medical University, China.
• Intern. Med. 2011 Jan 1; 50 (24): 294129452941-5.

ObjectiveThis study was undertaken to determine the relationship between red cell distribution width (RDW) and short-term outcomes in acute coronary syndrome (ACS) in a Chinese population.Methods And PatientsA total of 1,654 patients with ACS on admission were divided into four groups according to quartiles of baseline RDW. The relationships between RDW and one-month cardiac mortality as well as heart failure and recurrent infarction were assessed.ResultsHigher RDW values were associated with increased one-month cardiac mortality (quartile 1: 0.2%; quartile 2: 0.6%; quartile 3: 3.3%; quartile 4: 8.1%; p<0.001) and one-month heart failure and recurrent infarction (quartile 1: 2.1%; quartile 2: 2.7%; quartile 3: 3.6%; quartile 4: 15.2%; p<0.001). Logistic regression analysis revealed that RDW independently predicted for cardiac mortality (OR: 2.116, 95% CI: 1.427-3.137, p<0.001) and heart failure and recurrent infarction (OR: 2.134, 95% CI: 1.602-2.844, p<0.001) during a one-month follow-up in patients with ACS.ConclusionThe present study indicates that elevated RDW could predict an increased risk of short-term adverse outcomes in patients with ACS.

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