• Arch Orthop Trauma Surg · Aug 2011

    Calcium phosphate bone cement: a possible alternative to autologous bone graft. A radiological and biomechanical comparison in rat tibial bone.

    • Mona I Winge, Olav Reikerås, and Magne Røkkum.
    • Department of Orthopaedic Surgery, Rikshospitalet, Oslo University Hospital, Sognsvannveien 20, Oslo, Norway. mona.winge@oslo-universitetssykehus.no
    • Arch Orthop Trauma Surg. 2011 Aug 1; 131 (8): 103510411035-41.

    BackgroundDonor site morbidity is a problem after autologous bone transplantation. An injectable CaP bone cement indicates properties similar to bone.Materials And MethodsDouble osteotomies on rat tibias were performed. The intercalated segments were avascular (10), vascular (10), or avascular with Norian SRS(®) CaP bone cement replacing cancellous bone (10). Controls were non-operated contralateral tibias (15). All osteotomies were stabilised with an intra-medullary nail. After 8 weeks, all rats were killed. The harvested tibias were compared using X-ray, DEXA scanning, microCT scans and a biomechanical torsional test.ResultsNo difference in healing processes or biomechanical results has been found between the avascular bone graft, vascular bone graft and CaP bone cement groups.ConclusionThe injectable CaP bone cement confirms its similarities to bone, implying that it can be used as an adjunct to secure bone fragments and as a possible alternative to autologous bone transplantation in clinical practice.

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