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- Aaron Bangad, Mehdi Abbasi, Sam Payabvash, and Adam de Havenon.
- Department of Neurology, Yale University, New Haven, CT, USA.
- Neuroimaging Clin. N. Am. 2024 Feb 1; 34 (1): 167173167-173.
AbstractCerebral amyloid angiopathy (CAA) is a cerebrovascular disorder marked by the accumulation of amyloid-beta peptide (Aβ) within the leptomeninges and smaller blood vessels of the brain. CAA can be both noninflammatory and inflammatory, and the inflammatory version includes Aβ-related angiitis (ABRA). ABRA is a vasculitis of the central nervous system related to an inflammatory response to Aβ in the vascular walls, which necessitates differentiating ABRA from noninflammatory CAA, as ABRA may require immunosuppressive treatment. MR imaging is typically the most effective imaging modality of choice to screen for these conditions, and they should be obtained at varying time points to track disease progression.Copyright © 2023 Elsevier Inc. All rights reserved.
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