• Medicine · Mar 2024

    Case Reports

    Challenging diagnosis of male intraductal papilloma masquerading as eccrine hidradenoma in the breast: Case report.

    • Xinyue Liu, Jie Du, and Lirong Zhao.
    • Ultrasound Diagnostic Center, The First Hospital Affiliated to Jilin University, Changchun, Jilin, China.
    • Medicine (Baltimore). 2024 Mar 29; 103 (13): e37607e37607.

    RationaleThis article presents a challenging case involving an elderly male patient with a misdiagnosed intraductal mammary papilloma initially identified as a sweat adenoma through ultrasound imaging. The study aims to explore the histopathology, clinical presentations, and sonographic features of both conditions, emphasizing the contributing factors to the diagnostic misstep.Patient ConcernsA 61-year-old male reported a persistent left breast mass, along with pain and swelling, spanning a 6-month duration.DiagnosesUltrasound examination indicated a deep, square, mixed-echo mass in the left nipple, initially suggestive of a sweat adenoma. However, subsequent pathological analysis following resection under general anesthesia confirmed an intraductal papilloma.InterventionThe patient underwent surgical resection of the left breast mass under general anesthesia.OutcomePost-surgery, the patient exhibited satisfactory recovery; however, regrettably, he was lost to follow-up.LessonsThis study underscores the challenge in differentiating between clear cell sweat adenoma and male intraductal mammary papilloma solely based on ultrasonic characteristics. It emphasizes the susceptibility of ultrasound-based diagnoses to misinterpretation, highlighting the critical need for a comprehensive pathological examination to establish a definitive diagnosis.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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