• Filippo Giordano, Chiara Rutigliano, Caterina Ugolini, Erika Iacona, Lucia Ronconi, Celeste Raguseo, Teresa Perillo, Angarano Rosa, Nicola Santoro, and Ines Testoni.
• Department of Precision and Regenerative Medicine and Ionian Area (F.G.), University of Bari, Bari, Italy; Pediatric Hemathology-Oncology Unit (F.G., C.R., C.R., A.R., N.S.), University Hospital of Bari, Bari, Italy. Electronic address: filippo.giordano@uniba.it.
• J Pain Symptom Manage. 2024 Apr 27.

IntroductionThis study explores the feasibility and effects of music therapy on anticipatory nausea and vomiting, stress, pain and quality of life in adolescents undergoing chemotherapy.MethodsThis is a single group, quasi-experimental study using pre/post-test design. Participants received four individual sessions of music therapy (MT), led by a certified music therapist. State-Trait-Anxiety Inventory Y-1, and a 0-4 Likert scale for pain, nausea and vomiting were recorded. Heart rate variability (LF/HF) was collected during sessions. PedsQL was collected before and at the end of the trial. Semi-structured interviews were conducted with participants.ResultsA significant reduction in anxiety, nausea and vomiting, both pre-post single sessions and between different sessions, was observed. A significant increase in LF/HF and PedsQL scores was observed. Relevant themes also emerged from interviews.ConclusionResults support the feasibility of introducing music therapy with adolescents undergoing chemotherapy. Perceived stress and psychological/physical wellbeing were improved in participants.Copyright © 2024 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

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