• Dong Zeng, Jianghong Chen, Bo Zhu, Junke Li, Hongyu Wu, and Dan Ma.
• Institute of Cancer, Xinqiao Hospital, Third Military Medical University.
• Medicine (Baltimore). 2019 May 1; 98 (19): e15243e15243.

RationalPerianal Paget's disease (PPD) is a very rare intraepithelial adenocarcinoma. Very few cases of PPD have been reported till date, so the treatment remains controversial and more experience is needed.Patient ConcernsA 73-year-old female was admitted to several hospitals with diagnosed as "perianal eczema" in perianal lesion. After a variety of treatments, the patient's condition did not improve.DiagnosesAbdominopelvic computed tomography and rectal magnetic resonance imaging showed thickening of the soft tissue around the anus, with significant enhancement. Histologic examination revealed the state of Paget's cells.InterventionsLaparoscopic Extralevator Abdominoperineal Excision (ELAPE) surgery was performed at our department.OutcomesThe patient recovered well. After 10 months, a check-up revealed that her perianal area was disease-free.LessonsThe aim of this report was to present the characteristics of PPD in order to improve its diagnosis and treatment. Laparoscopic ELAPE is a successful therapy.

16 keywords...

hide…