• Lingjuan Liu, Miao Li, Minhua Hu, Zhilin Ge, and Xiulan Dong.
• The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
• Medicine (Baltimore). 2024 Nov 29; 103 (48): e40747e40747.

RationalePsoriasis is an immune-mediated, chronic, relapsing, inflammatory disease induced by a combination of genetic and environmental factors. It can be comorbid with other systemic diseases and severely affects patient's quality of life. This case report describes the therapeutic role of traditional Chinese medicine (TCM) in patient with psoriasis.Patient ConcernsThe 32-year-old male patient exhibited symptoms of increased dandruff and recurrent erythematous scales on various body regions for nearly a year. At the same time, he had multisystemic metabolic abnormalities and psychiatric disorders.DiagnosisSevere plaque psoriasis.InterventionsThe patient was treated with oral Chinese herbal medicine only.OutcomesFollowing TCM treatment, the patient demonstrated significant improvement in his skin condition and various metabolic-related indexes.LessonsTCM is involved in the harmonization of yin and yang, regulation of qi and blood, dispersion of pathogenic wind, cooling of blood, and alleviation of blood stasis. From a modern medical perspective, TCM prescriptions may address skin inflammation by restoring physiological functions and enhancing immune response. This case study illustrates the efficacy of TCM in treating skin disorders and enhancing the body's internal environment.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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