• XuHui Wang, Xinghua Gao, and LongYang Zhang.
• School of Clinical Medicine, Shandong Second Medical University, Weifang, China.
• Medicine (Baltimore). 2024 Nov 29; 103 (48): e40757e40757.

RationaleSpermatic cord myxomas are rare benign tumors, typically characterized by the production of mucopolysaccharides. These tumors are infrequently found in the urinary system, making this case noteworthy.Patient ConcernsA 55-year-old male presented with a painless swelling on the right side of his scrotum, which had persisted for over 3 months. There were no associated symptoms, and the patient had no significant medical history.DiagnosesInitial diagnostic workup included physical examination, ultrasonography, and CT scans, which revealed a 2 cm cystic nodule near the right spermatic vein. Postoperative histopathology confirmed the diagnosis of myxoma.InterventionsThe patient underwent laparoscopic high ligation of the left spermatic vein and excision of the right spermatic sheath cyst. The surgery was successful, with the cyst being completely removed.OutcomesPostoperative recovery was uneventful, and histopathological examination confirmed the benign nature of the tumor. Follow-up was advised to monitor for any recurrence.LessonsAlthough rare, spermatic cord myxomas should be considered in the differential diagnosis of scrotal masses. Surgical excision is both diagnostic and therapeutic, providing a favorable prognosis with minimal risk of recurrence.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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