• Ning Wang, Li Zhang, WangShuoSDepartment of Radiological and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China., Xiang-Yang Chang, Bao-Gen Zhao, and Yong Wang.
• Department of Radiological and Nuclear Medicine, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
• Medicine (Baltimore). 2024 Nov 29; 103 (48): e40656e40656.

BackgroundTo investigate the clinical features, imaging manifestations, and pathological characteristics of mixed epithelial stromal tumor of the kidney (MESTK) to improve the understanding of MESTK and the accuracy of preoperative imaging diagnosis.MethodsThe clinical, imaging, and pathological data of 3 patients with MESTK confirmed by postoperative pathology were retrospectively analyzed.ResultsThree patients with MESTK were middle-aged women with no obvious clinical symptoms. The main image representation showed a multilocular cystic or solid-cystic mass, with the larger masses protruding from the kidney contour, with multiple separations, which could be of unequal thickness. The cystic component showed no enhancement on enhancement scans, whereas the segregations and solid components showed gradual and obvious enhancement. Microscopic pathology was characterized by the biphasic differentiation of mesenchymal and epithelial components.ConclusionMESTK is a rare, mostly benign tumor that appears as a multilocular cystic or cystic solid, with progressive marked enhancement of the septal and solid components on enhanced scans. This imaging feature is helpful for the diagnosis of MESTK.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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