• Qingbao Zhu, Lei Ye, Liao Guan, Xuefei Ji, Ziao Xu, and Hongwei Cheng.
• Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei, PR China; Department of Neurosurgery, Maanshan People's Hospital, Maanshan, PR China.
• World Neurosurg. 2025 Jan 24; 195: 123637123637.

ObjectiveTo determine the prognostic impacts of the characteristics in routine plasma and blood tests for patients with traumatic brain injury (TBI).MethodsA total of 136 consecutive adult patients with TBI were recruited. Blood and plasma routine tests were performed within 24 hours from admission. All patients were briefly followed up at the third month after discharge. We analyzed the prognostic factors with univariate and multifactor logistic regression models in the patients receiving surgical and conservative treatments, respectively.ResultsWe found different prognostic factors in the patients receiving diverse treatments. In the patients receiving surgical treatment, infection is the only influencing factor, while in the patients receiving conservative treatment, age (P = 0.004), white blood cell count (WBC) (P = 0.008), and albumin (P = 0.040) were the independent factors of prognosis. In the receiver operator characteristic analysis, the values of area under the curve of these factors were 0.788 for age, 0.695 for WBC, and 0.709 for albumin, respectively. The combined area under the curve of the 3 factors was 0.898.ConclusionsTBI patients receiving diverse treatments might have different pathophysiologic conditions and different influencing factors of prognosis.Copyright © 2025 The Authors. Published by Elsevier Inc. All rights reserved.

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