• Dermatology (Basel) · Jan 2013

    Randomized Controlled Trial Comparative Study

    Management of split-thickness skin graft donor sites: a randomized controlled trial of calcium alginate versus polyurethane film dressing.

    • Severin Läuchli, Jürg Hafner, Sonja Ostheeren, Dieter Mayer, Marjam J Barysch, and Lars E French.
    • Dermatologische Klinik, Universitätsspital Zürich, Zürich, Switzerland.
    • Dermatology (Basel). 2013 Jan 1;227(4):361-6.

    BackgroundSplit-thickness skin graft (STSG) donor sites sometimes cause more postoperative morbidity for patients than the wound covered with the graft. Yet, there is no consensus on which dressings are best suited to treat these donor sites.ObjectiveTo evaluate two commonly used modern wound dressings in the postoperative healing of STSG donor sites in a prospective randomized controlled trial.Methods38 patients were randomly assigned to treatment of an STSG donor site with an alginate dressing or a polyurethane film dressing. The primary outcome measures were postoperative pain scores, secondary outcome variables were time to epithelialization, dressing changes and complications.ResultsPostoperative pain on day 1 was significantly lower in the polyurethane film group (2.05 vs. 0.79, p = 0.035) as compared to the alginate group. This difference was not detected on day 5 (0.89 vs. 0.53, p = 0.52). Time to epithelialization did not differ significantly between the two dressing groups. There were more dressing changes in the polyurethane film group and problems with leakage.ConclusionWhereas film dressings resulted in initially lower pain scores, alginate dressings caused fewer additional dressing changes and less leakage.

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