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Arch Orthop Trauma Surg · Jan 2000
Clinical TrialReduction of blood loss using tranexamic acid in total knee and hip arthroplasties.
- K Ido, M Neo, Y Asada, K Kondo, T Morita, T Sakamoto, R Hayashi, and S Kuriyama.
- Department of Orthopaedic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan.
- Arch Orthop Trauma Surg. 2000 Jan 1; 120 (9): 518-20.
AbstractThere have been several attempts to reduce postoperative blood loss in patients undergoing total arthroplasty. Benoni et al. reported the usefulness of tranexamic acid in total knee arthroplasty (TKA). We investigated its effect in TKA and total hip arthroplasty (THA). Blood loss was significantly reduced in patients given tranexamic acid in both the TKA and THA groups, and no severe complications, such as venous or pulmonary thrombosis, were noted in any of the patients who received the agent. Administration of tranexamic acid seems to be useful for reducing postoperative blood loss in TKA and THA.
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