• Am J Emerg Med · Mar 2016

    Review

    Treating appendicitis with antibiotics.

    • Itzhak Brook.
    • Department of Pediatrics, Georgetown, University School of Medicine Washington DC. Electronic address: ib6@georgetown.edu.
    • Am J Emerg Med. 2016 Mar 1; 34 (3): 609-10.

    AbstractA nonsurgical approach using antimicrobial agents has been advocated as the initial treatment of uncomplicated appendicitis. Several studies and meta-analyses explored this approach. Because many of these studies included individuals with resolving appendicitis, their results were biased. Antimicrobials, however, are warranted and needed for the management of surgical high-risk patients with perforated appendicitis and those with localized abscess or phlegmon. Randomized placebo-controlled trials that focus on early identification of complicated acute appendicitis patients needing surgery and that prospectively evaluate the optimal use of antibiotic treatment in patients with uncomplicated acute appendicitis are warranted.Copyright © 2015 Elsevier Inc. All rights reserved.

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