• A Piatkowski, N Drummer, A Andriessen, D Ulrich, and N Pallua.
• Department of Plastic Surgery and Hand Surgery-Burn Unit, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52057 Aachen, Germany. apiatkowski@ukaachen.de
• Burns. 2011 Aug 1;37(5):800-4.

ObjectiveA prospective, randomized, controlled single center study was designed to evaluate clinical efficacy of a polyhexanide containing bio-cellulose dressing (group B) compared to a silver-sulfadiazine cream (group A) in sixty partial-thickness burn patients.Patients And MethodsLocal ethics committee approval was obtained and patients consented. Parameters were: pain reduction (VAS), healing time and wound bed condition, comparing day 0 (start) versus day 14 (end), as well as, ease of dressing use and treatment costs.ResultsAll completed the study (n=30/n=30) and were included in the ITT analysis, with a total of 72 burns (group A: n=38, group B: n=34). We noted no differences in healing time. Pain reduction was significantly faster and better in group B (p<0.01). There were fewer dressing changes in group B, compared to group A. Ease of use for the bio-cellulose dressing was rated better compared to group A. In group B, € 95.20 was saved for a 10 day treatment period, compared to group A.ConclusionGroup B demonstrated a better and faster pain reduction in the treated partial-thickness burns, compared to group A. The results indicate the polyhexanide containing bio-cellulose dressing to be a safe and cost effective treatment for partial-thickness burns.Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

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