• Katherine Mandeville, Tamara Pottker, Blake Bulloch, and Jiexin Liu.
• Department of Emergency Medicine, Phoenix Children's Hospital, Phoenix, AZ 85016, USA.
• Am J Emerg Med. 2011 Nov 1;29(9):972-7.

Study ObjectiveThe aims of the study were to prospectively evaluate the Alvarado and Samuel (pediatric appendicitis score [PAS]) appendicitis scoring systems in children and determine performance based on sex.MethodsChildren with abdominal pain concerning for appendicitis were recruited. Nine parameters evaluated by the scores were documented before imaging/surgery consultation. Test characteristics were calculated on all patients and by sex.ResultsTwo hundred eighty-seven patients enrolled; median age was 9.8 years; and 155 (54%) were diagnosed with pathologic examination-confirmed appendicitis. Patients with appendicitis had mean PAS of 7.6, and those without had mean of 5.6 (P < .001). Patients with appendicitis had a mean Alvarado of 7.2, and those without had a mean of 5.2 (P < .001). In appendicitis patients, PAS cutoff of 6 or greater would give 137 correct diagnoses; sensitivity, 88%; specificity, 50%; and positive predictive value (PPV), 67%. An Alvarado cutoff of 7 or greater would give 118 correct diagnoses; sensitivity, 76%; specificity, 72%; and PPV, 76%. Both performed better in males than females.ConclusionRegardless of sex, neither PAS nor Alvarado has adequate predictive values for sole use to diagnose appendicitis.Copyright © 2011 Elsevier Inc. All rights reserved.

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