• Anaesthesia · Sep 1997

    Randomized Controlled Trial Comparative Study Clinical Trial

    The addition of opioids to local anaesthetics in brachial plexus block: the comparative effects of morphine, buprenorphine and sufentanil.

    • J E Bazin, C Massoni, P Bruelle, V Fenies, D Groslier, and P Schoeffler.
    • Département d'Anaesthésie et de Réanimation, Hôpital Universitaire G. Montpied, Clermont-Ferrand, France.
    • Anaesthesia. 1997 Sep 1;52(9):858-62.

    AbstractWe compared the duration of analgesia produced by a mixture of lignocaine and bupivacaine, either alone or combined with morphine (75 micrograms.kg-1), buprenorphine (3 micrograms.kg-1) or sufentanil (0.2 microgram.kg-1) in 80 patients after brachial plexus block for orthopaedic surgery of the upper limb. The characteristics of analgesia were evaluated hourly using a visual analogue scale. The analgesia was considered satisfactory for scores of 30 or less. The median duration (range) of satisfactory analgesia was: 11.5 (8-15) h without an opioid, 21 (9-27) h with morphine, 20 (14-34) h with buprenorphine and 24.5 (11-38) h with sufentanil. We conclude that the addition of an opioid to a local anaesthetic mixture lengthens the duration of analgesia.

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