• Anaesthesia · Feb 2011

    Case Reports

    Hyperglycaemia and cerebral oedema in a patient with a meningioma receiving dexamethasone.

    • S Ramessur, J Dinsmore, and A Zoumprouli.
    • St George's Hospital NHS Trust, London, UK.
    • Anaesthesia. 2011 Feb 1;66(2):127-31.

    AbstractDexamethasone is prescribed routinely to reduce cerebral oedema in neurosurgical patients undergoing craniotomy for tumour and is used increasingly as an anti-emetic. Dexamethasone, however, has been shown to cause hyperglycaemia. We describe a case of hyperglycaemic crisis, cerebral oedema and death secondary to dexamethasone in a patient with a frontal meningioma. We highlight the risks of peri-operative dexamethasone and discuss the diagnosis, treatment and complications of hyperglycaemic crises and cerebral oedema.© 2010 The Authors. Anaesthesia © 2010 The Association of Anaesthetists of Great Britain and Ireland.

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