• Anaesthesia · Feb 1988

    Randomized Controlled Trial Comparative Study Clinical Trial

    Intrathecal buprenorphine for postoperative analgesia in the elderly patient.

    • G Capogna, D Celleno, V Tagariello, and C Loffreda-Mancinelli.
    • Department of Anaesthesiology and Intensive Care, Ospedale S. Giovanni Calibita Fatebenefratelli.
    • Anaesthesia. 1988 Feb 1;43(2):128-30.

    AbstractNinety patients aged 56-85 years scheduled for suprapubic prostatectomy, randomly received intrathecally either bupivacaine 30 mg (group A, n = 30), bupivacaine 30 mg plus buprenorphine 0.03 mg (group B, n = 30) or bupivacaine 30 mg plus buprenorphine 0.045 mg (group C, n = 30). Prolonged postoperative analgesia, minimal disturbance of consciousness and comfortable breathing were common to the groups that received buprenorphine. The higher concentration of buprenorphine improved the quality and duration of analgesia. The only side effects found in the buprenorphine groups were nausea and vomiting in 11 and 14 patients, respectively, in groups B and C. Our study shows that buprenorphine is an effective analgesic, suitable for the management of postoperative pain in elderly patients.

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