• Ophthalmologica · May 2005

    Randomized Controlled Trial Comparative Study Clinical Trial

    Lidocaine gel versus combined topical anesthesia using bupivacaine, oxybuprocaine and diclofenac eyedrops in cataract surgery.

    • Michelle Thill, Oliver Zeitz, Ines Richard, and Gisbert Richard.
    • Department of Ophthalmology, University Hospital Hamburg-Eppendorf, Hamburg, Germany. mthill@uke.uni-hamburg.de
    • Ophthalmologica. 2005 May 1;219(3):167-70.

    PurposeTo assess the safety and efficacy of two topical anesthesia regimes for cataract surgery.Methods21 patients received a combination of 4 times bupivacaine 0.5, oxybuprocaine and diclofenac eyedrops, 18 patients were given a single topical application of lidocaine gel 2%. A single intracameral injection of lidocaine 1% was administered to all subjects.ResultsThe extent to which the surgeon was bothered by patient motility was graded as low in about two thirds of all procedures. Patients reported lower intraoperative pain levels with a single application of lidocaine gel supplemented with intracameral lidocaine than with a fourfold application of the combination topical anesthesia plus intracameral anesthesia.ConclusionsA single application of lidocaine gel 2% combined with intracameral anesthesia provides at least as good analgesia than multiple administration of combined topical anesthesia supplemented with intracameral anesthesia and is equally safe.

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