• Suh-Hwa Maa, Tzong-Jen Hung, Kuang-Hung Hsu, Ya-I Hsieh, Kwua-Yun Wang, Chun-Hua Wang, and Horng-Chyuan Lin.
• School of Nursing, Chang Gung University, 259, Wen-Hwa First Rd, Kwei-San, Tao-Yuan, Taiwan, ROC. shmaa@mail.cgu.edu.tw
• Chest. 2005 Oct 1;128(4):2714-21.

Study ObjectivesTo investigate the effect of manual hyperinflation (MH) in patients with atelectasis associated with ventilation support.DesignPatients were randomized to either an experimental group or a control group.SettingPulmonary ICUs from two hospitals.PatientsTwenty-three patients with atelectasis associated with ventilation support.InterventionsThe MH technique was at a rate of 8 to 13 breaths/min for a period of 20 min each session, three times per day for 5 days. The control group received their standard prescribed mechanical ventilation without supplemental MH. Sputum contents (wet/dry weight ratio, viscosity), respiratory system capacity (spontaneous tidal volume [Vt], maximal inspiratory pressure, rapid shallow breathing index [f/Vt], chest radiograph signs, and Pa(O2)/fraction of inspired oxygen [Fi(O2)]) were measured just prior to the MH at day 0 as baseline, and at day 3 and day 6 of the study.Measurements And ResultsThere were significant improvements in scores over the 6-day study in the experimental group compared to the control group in spontaneous Vt (p = 0.035) and chest radiograph signs (p = 0.040), and a trend toward improvement of f/Vt (p = 0.066) and Pa(O2)/Fi(O2) (p = 0.061) after adjustment for covariates. Other outcome variables did not differ significantly between the experimental and control groups.ConclusionsMH performed on patients with atelectasis from ventilation support significantly improved alveolar recruitment.

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