• Magn Reson Imaging · Sep 2014

    Distinguishing and quantification of the human visual pathways using high-spatial-resolution diffusion tensor tractography.

    • Arash Kamali, Khader M Hasan, Pavani Adapa, Azadeh Razmandi, Zafer Keser, John Lincoln, and Larry A Kramer.
    • Department of Diagnostic Radiology, University of Medicine and Dentistry of New Jersey Cooper, Camden, NJ, USA.
    • Magn Reson Imaging. 2014 Sep 1;32(7):796-803.

    AbstractQuantification of the living human visual system using MRI methods has been challenging, but several applications demand a reliable and time-efficient data acquisition protocol. In this study, we demonstrate the utility of high-spatial-resolution diffusion tensor fiber tractography (DTT) in reconstructing and quantifying the human visual pathways. Five healthy males, age range 24-37years, were studied after approval of the institutional review board (IRB) at The University of Texas Health Science Center at Houston. We acquired diffusion tensor imaging (DTI) data with 1-mm slice thickness on a 3.0-Tesla clinical MRI scanner and analyzed the data using DTT with the fiber assignment by continuous tractography (FACT) algorithm. By utilizing the high-spatial-resolution DTI protocol with FACT algorithm, we were able to reconstruct and quantify bilateral optic pathways including the optic chiasm, optic tract, optic radiations free of contamination from neighboring white matter tracts.Copyright © 2014 Elsevier Inc. All rights reserved.

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