• Wien Med Wochenschr · Apr 1990

    Review

    [How do beta receptor blockers modify physical performance and metabolism?].

    • W Kindermann.
    • Institut für Sportmedizin, Universität des Saarlandes, Saarbrücken, BRD.
    • Wien Med Wochenschr. 1990 Apr 15;140(6-7):170-6.

    AbstractBeta-blockers reduce physical capacity and lead to an increased sensation of muscular fatigue. The limits of endurance capacity, which is important for both leisure-sports and fitness, are set primarily by metabolic factors, because the energy liberation via the metabolism of lipids and carbohydrates is reduced as a result of the inhibition of lipolysis and glycogenolysis. Beta 1-selective blockers influence the physical capacity less effectively on any intensity level as non-selective blockers do. The latter may lead to hypoglycemic reactions. Beta-blockers with intrinsic sympathicomimetic activity (ISA) are not superior to others. Physically active patients should be treated with beta 1-selective blockers.

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