Wiener medizinische Wochenschrift
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Wien Med Wochenschr · Apr 1990
Review[Performance modification in sports by beta receptor blockers].
Beta-adrenoceptor-blockers modify the physical performance due to their haemodynamic and metabolic effects. Additionally, these substances influence the concentration of serum-potassium and the thermoregulation. The reduction in heart rate yields to a diminished cardiac output resulting in a restricted muscular blood flow at submaximal and maximal exercise. ⋯ Arterial peak lactate concentration usually is diminished. After beta-adrenoceptor-blockade, the concentration of serum-potassium increases slightly, and sweat production is enhanced. Beta-adrenoceptor-blockers influence the performance in different sports to a various extent, due to the multitude of the different effects they take.
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Wien Med Wochenschr · Apr 1990
Review[How do beta receptor blockers modify physical performance and metabolism?].
Beta-blockers reduce physical capacity and lead to an increased sensation of muscular fatigue. The limits of endurance capacity, which is important for both leisure-sports and fitness, are set primarily by metabolic factors, because the energy liberation via the metabolism of lipids and carbohydrates is reduced as a result of the inhibition of lipolysis and glycogenolysis. ⋯ Beta-blockers with intrinsic sympathicomimetic activity (ISA) are not superior to others. Physically active patients should be treated with beta 1-selective blockers.