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- K N Litchfield, J M Harten, K J Anderson, J Kinsella, and E M McGrady.
- Southern General Hospital, Department of Anaesthesia, 1345 Govan Road, Glasgow G51 4TF, UK. klitchfield@doctors.org.uk
- Anaesthesia. 2007 Sep 1;62(9):931-5.
AbstractFifteen healthy, full-term women with singleton pregnancies were exposed to an increased F(I)o(2) of 0.4 and their haemodynamic responses measured with a non-invasive transthoracic bio-impedance monitor. There was a mean reduction in cardiac index from 3.18 to 3.03 l x min(-1) x m(-2) (4.7%, p = 0.004). The mean indexed systemic vascular resistance increased from 2049 to 2178 dynes x cm(-5) x m(-2) (5.7%, p = 0.005). There were no significant changes in stroke index, heart rate or mean arterial pressure. This study demonstrates that even a moderate increase in inspired oxygen fraction has significant effects on the cardiovascular system of the term parturient.
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